Female breast cancer mortality in the American continent: temporal trends

Lucas C. Passoni-Lopes, Department of Medicine, Faculdade de Medicina de Bauru, Universidade de São Paulo, São Paulo, Brazil

Introduction: Female breast cancer (FBC) is the most prevalent malignancy among women worldwide and represents a significant public health challenge. Its mortality trends remain a debatable issue across American countries. Objective: The objective of the study was to evaluate the temporal trends of FBC mortality in America. Material and methods: This ecological study analyzed temporal trends in FBC mortality in America from 2000 to 2019. All data were obtained from the Pan-American Health Organization and were analyzed with the Jointpoint 5.4.0®. Results: North America saw declining mortality trends in Canada and the United States, while Mexico exhibited an increase. In Central America, trends varied, with some countries showing rising mortality, others experiencing declines, and some displaying complex patterns of fluctuation. South America and Insular America countries presented decreasing trends in FBC mortality, but some regional disparities remain significantly. Conclusion: This study highlights significant temporal trends in American FBC mortality, identifying critical areas for public health intervention and offering a foundation for future research on healthcare equity and cancer outcomes.

Keywords: Breast cancer. Women. America.